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scion corporation pc-based software scion image
Pc Based Software Scion Image, supplied by scion corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pc-based+software+scion+image/pc+based+software+scion+image/pmc08836014-208-9-11
Average 90 stars, based on 1 article reviews
pc-based software scion image - by Bioz Stars, 2026-09
90/100 stars

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Article Title: Depressive- and anxiety-like behaviors and stress-related neuronal activation in vasopressin-deficient female Brattleboro rats.
Article Snippet: Article history: Received 11 November 2015 Received in revised form 24 February 2016 Accepted 27 February 2016 Available online 03 March 2016 Vasopressin can contribute to the development of stress-related psychiatric disorders, anxiety and depression.. Although these disturbances are more common in females, most of the preclinical studies have been done in males.. We compared female vasopressin-deficient and+/+Brattleboro rats.

Article Title: The brain pattern of c-fos induction by two doses of amphetamine suggests different brain processing pathways and minor contribution of behavioural traits.
Article Snippet: bstract—Previous studies have shown that amphetamine AMPH) markedly activates dopaminergic projection areas, ogether with some important limbic nuclei.. However, a lobal picture of the brain areas activated is lacking and the ontribution of the dose of the drug and individual differnces to this global brain activation is not known.. In the resent experiment, we studied in adult male rats the c-fos xpression induced by two doses of AMPH (1.5 and 5 mg/kg c) in a wide range of brain areas, and investigated the posible contribution of novelty-induced activity and anxiety raits.

Article Title: Brain pattern of histone H3 phosphorylation after acute amphetamine administration: its relationship to brain c-fos induction is strongly dependent on the particular brain area.
Article Snippet: Recent evidence strongly suggests a critical role of chromatin remodelling in the acute and chronic effects of addictive drugs.. We reasoned that Immunohistochemical detection of certain histone modifications may be amore specific tool than induction of immediate early genes (i.e. c-fos) to detect brain areas and neurons that are critical for the action of addictive drugs.. Thus, in the presentworkwe studied in adultmale rats the effects of a high dose of amphetamineonbrainpattern of histoneH3 phosphorylation in serine10 (pH3S10) and c-fos expression.

Article Title: Rescue of Vasopressin Synthesis in Magnocellular Neurons of the Supraoptic Nucleus Normalises Acute Stress-Induced Adrenocorticotropin Secretion and Unmasks an Effect on Social Behaviour in Male Vasopressin-Deficient Brattleboro Rats
Article Snippet: To select c-Fos immunopositive nuclei as targets for quantification, PC-based software (Scion Image, Scion Corporation, Frederick, MD, USA) was used and targets were subsequently identified in the captured images by grey level thresholding.

Article Title: Immediate-early gene response to repeated immobilization: Fos protein and arc mRNA levels appear to be less sensitive than c-fos mRNA to adaptation.
Article Snippet: Stress exposure resulted in brain induction of immediate-early genes (IEGs), considered as markers of neuronal activation.. Upon repeated exposure to the same stressor, reduction of IEG response (adaptation) has been often observed, but there are important discrepancies in literature that may be in part related to the particular IEG and methodology used.. We studied the differential pattern of adaptation of the IEGs c-fos and arc (activity-regulated cytoskeleton-associated protein) after repeated exposure to a severe stressor: immobilization on wooden boards (IMO).

Article Title: High doses of the histone deacetylase inhibitor sodium butyrate trigger a stress-like response.
Article Snippet: The hypothalamicepituitaryeadrenal (HPA) axis is activated by a wide range of stimuli, including drugs.. Here we report that in male rats, a dose of sodium butyrate (NaBu) that is typically used to inhibit histone deacetylation (1200 mg/kg) increased the peripheral levels of HPA hormones and glucose.. In a further experiment, we compared the effects of two different doses of NaBu (200 and 1200 mg/kg) and equimolar saline solutions on peripheral neuroendocrine markers and brain c-Fos expression to demonstrate a specific stress-like effect of NaBu that is not related to hypertonicity and to localise putatively involved brain areas.

Article Title: Stress-induced brain histone H3 phosphorylation: contribution of the intensity of stressors and length of exposure.
Article Snippet: To select pH3S10 positive and pH3S28 positive immunopositive nuclei as targets for quantification, PC-based software (Scion Image; Scion Corporation, Frederick, MD, USA) was used and targets were subsequently identified in the captured images by gray level thresholding (Rotllant et al. 2010).

Article Title: Peripuberty stress leads to abnormal aggression, altered amygdala and orbitofrontal reactivity and increased prefrontal MAOA gene expression
Article Snippet: To select c‐Fos immunopositive nuclei for quantification, PC‐based software (Scion Image, Scion Corporation, Frederick, MD, USA) was used, and the nuclei were subsequently identified in the captured images by gray‐level thresholding.



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